Twyla (also Twila) is a feminine given name. Notable people with the name include:
Twyla Twyla Baker (born 1976), American Indian academic administrator Twyla Hansen (born 1949), American poet, a Nebraska State Poet Twyla Herbert (1921–2009), American songwriter Twyla Mason Gray (1954–2011), American politician from Oklahoma Twyla Roman (born 1941), American politician from Ohio Twyla Tharp (born 1941), American dancer, choreographer, and author Twyla Sands, a character on the television series Schitt's Creek Twyla, the daughter of a boogeyman from Monster High
Twila
Twila Herr (1946–2007), American-born Australian librarian and educator
Twila Paris (born 1958), American singer-songwriter, author, and pianist Twila Shively (1920–1999), American baseball outfielder Twila, a character from the video game Mario Party 6