Doyne is a surname. Notable people with the surname include:
Cory Doyne (born 1981), Major League Baseball pitcher who is currently in the Washington Nationals organization John Doyne (1912–1997), Wisconsin politician and the first County Executive of Milwaukee County, Wisconsin Maggie Doyne (born 1987), American philanthropist who has built an orphanage, women's centre and school in the Kopila Valley of Nepal Philip Doyne (1886–1959), British fencer Robert Walter Doyne (1857–1916), British ophthalmologist Sir Robert Doyne (1651–1733), member of the Irish House of Commons, and later a distinguished judge Geoffrey Doyne Adams KCMG OBE (born 1957), member of the British Diplomatic Service J. Doyne Farmer (born 1952), American physicist and entrepreneur, with interests in chaos theory, complexity and econophysics William Thomas Doyne (1822–1877), Irish engineer active in the Crimean War
See also O Doyne manuscript, collection of material relating to a dispute among the Gaelic-Irish family of Ó Duinn Ardoyne Dyne Oyne