Issac is a spelling variant of the name Isaac.
Issac may refer to:
Given name Issac Bailey, American writer Issac Blakeney (born 1992), American football wide receiver Issac Booth (born 1971), American football player Issac Ryan Brown (born 2005), American child actor and singer Issac Delgado (born 1962), Cuban-Spanish musician, and salsa performer Issac Koga (1899–1982), Japanese electronics researcher/engineer Issac Luke (born 1987), New Zealand rugby league hooker Issac Osae (born 1993), Ghanaian footballer
Surname Osthatheos Issac (born 1976), Syriac Orthodox bishop Rod Issac (born 1989), American football cornerback
Other Issac, Dordogne, a commune in France Issacs Building, in Los Angeles, California
See also Isaac (name) Isaac (disambiguation)