Topcliffe may refer to:
Places Topcliffe, North Yorkshire, a village and civil parish in England Topcliffe Castle, an abandoned castle Topcliffe railway station (closed) RAF Topcliffe, a Royal Air Force station Topcliffe, West Yorkshire, a United Kingdom location in Morley, Leeds
People John Topcliffe (died 1513), English-born judge Richard Topcliffe (1531–1604), English priest hunter