Bitter Creek may refer to:

Bitter Creek, Texas, a ghost town in Nolan County Bitter Creek (South Dakota) Bitter Creek (Utah), a tributary of the White River Bitter Creek (Wyoming), a tributary of the Green River Bitter Creek National Wildlife Refuge, in Kern County, California Bitter Creek (film), a 1954 American Western film Bitter Creek, a song from the Eagles' album Desperado George “Bittercreek” Newcomb, a member of the Wild Bunch