Lofa may refer to:

Lofa County, a county in Liberia Lofa Defense Force or LDF, a rebel group that participated in the Liberian Civil War Lofa River, a river in Liberia Lofa Tatupu (Mosiula Mea'alofa "Lofa" Tatupu, born 1982), American football linebacker Lofa-Mano National Park, a proposed national park in Liberia League of Oran Football Association (LOFA): former departemental football governing body under the french colonial period of Algeria Leap of Faith Assumption, a concept of the Lean startup business development process

See also Lofanga, an island in Tonga