Sheff may refer to:

People: David Sheff, American author of books Don Sheff (born 1931), American former competition swimmer Robert Nathan Sheff (born 1945), avant-garde composer and pianist Stanley Sheff, Hollywood-born director and writer Will Sheff (born 1976), the frontman for the Austin, Texas-based indie band Okkervil River

Other: Sheff, Indiana, an extinct town Sheffield, a city in England, sometimes called 'Sheff' Sheff v. O'Neill, a 1989 lawsuit and the subsequent 1996 Connecticut Supreme Court case Gluskin Sheff (TSX: GS), a Canadian independent wealth management firm

See also Sheff. Star or Sheffield Star, a daily newspaper published in Sheffield, England Sheff U or Sheffield United F.C., professional football club in Sheffield, South Yorkshire, England Sheff Wed or Sheffield Wednesday F.C., football club in Sheffield, South Yorkshire, England Scheff