Briles is a surname. Notable people with the name include:
Art Briles (born 1955), American football player and coach Herschel F. Briles (1914–1994), US Army soldier James E. Briles (1926–1992), American politician Judith Briles, American author Kendal Briles (born 1982), American football player and coach Nelson Briles (1943–2005), American baseball player