Vilhena is a municipality in Rondônia, Brazil.
Vilhena may also refer to:
Vilhena Esporte Clube, a football club in Vilhena, Brazil Vilhena Airport, an airport in Vilhena, Brazil Macasinia vilhena, a moth found in Rondônia, Brazil
Places Floriana, a town in Malta also known as Borgo Vilhena Villena, a city in Valencia, Spain Palazzo Vilhena, a palace in Mdina, Malta
People , Spanish noble family Sancho Manoel de Vilhena, a Portuguese aristocrat and military leader António Manoel de Vilhena, a Portuguese aristocrat and Grand Master Tonny Vilhena, a Dutch footballer