Brainless may refer to:

"Brainless", a 1995 song by The Urge, from the album Receiving the Gift of Flavor "Brainless", a 2013 song by Eminem, from the album The Marshall Mathers LP 2 "Brainless", an episode of Round the Twist, 2000 See also Anencephaly, the absence of a major portion of the brain, skull, and scalp that occurs during embryonic development.