Charles Clough may refer to:
Charles Clough (artist) (born 1951), American painter Charles Clough (geologist) (1852–1916), British geologist and mapmaker Charles A. Clough (1903–1961), American prelate of the Episcopal Church Charlie Clough (born 1990), English footballer Charles F. Clough (1843–1927), American politician, mayor of Spokane, 1890–1891