William Pennington (1796–1862) was an American politician who served as Governor of New Jersey and Speaker of the House.
William Pennington may also refer to:
William Sanford Pennington (1757–1826), American politician and judge, father of the above William George Pennington, 19th-century Australian politician William Henry Pennington (1833-1923), British soldier and actor William Pennington (businessman) (1923–2011), American casino executive