Byrns is a surname. Notable people with the surname include:
Elinor Byrns (1876–1957), American lawyer and pacifist, co-founder of the Women's Peace Society Harold Byrns (1903–1977), German-American conductor and orchestrator Joseph W. Byrns Jr. (1903–1973), U.S. attorney and politician Jo Byrns (1869–1936), U.S. Democratic politician Samuel Byrns (1848–1914), U.S. member of Congress from Missouri
See also Burns (surname) Byrne Byrnes Bryne (disambiguation) Daniel and Nellie Byrns House