Bacterial thiol disulfide oxidoreductases (TDOR) are bacterial enzymes that participate in redox reactions involving cysteine residues. Along with unfolded proteins, they are secreted from bacterial cells into periplasmic spaces or extracellularly, and may have membrane anchors. Some have functions in promoting processes of adhesion and biofilm development, and generally disease development.
Table Enzyme name Meaning Bacteria Catalytic site DsbA D disulfide bond A various incl. Staphylococcus aureus CXXC DsbA D disulfide bond A Escherichia coli CPHCBdbA–D Bacillus subtilis MdbA Actinomyces oris, Corynebacterium diphtheriae CPHC SdbA Streptococcus gordonii
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