M16 is a family of military rifles.
M16 or M-16 may also refer to:
Firearms and military M16 mine, an American landmine BOV M16 Miloš, a Serbian 4x4 multipurpose armoured vehicle Flammenwerfer M.16., a German First World War flamethrower Fokker M.16, a 1915 German biplane , a First World War Royal Navy M15-class monitor Grigorovich M-16, a Russian World War I–era biplane flying boat Stahlhelm, a German World War I helmet M16 (rocket), an American artillery rocket of World War II and the Korean War M16 Multiple Gun Motor Carriage, an American self-propelled anti-aircraft weapon
Transportation
Aerospace John Bell Williams Airport, in Raymond, Mississippi Magni M-16 Tandem Trainer, an Italian autogyro introduced in 2000 Macchi M.16, an Italian biplane built in 1919 Miles M.16 Mentor, a 1930s British monoplane Progress M-16, a Russian spacecraft
Surface Vehicles M16 (New York City bus), a former New York City Bus route in Manhattan M Scow (M-16), a 16-foot sailboat McLaren M16, an IndyCar race car Midland M16, a Formula One car run by Midland F1 in 2006
Roads M16 (East London), a Metropolitan Route in East London, South Africa M16 (Cape Town), a Metropolitan Route in Cape Town, South Africa M16 (Johannesburg), a Metropolitan Route in Johannesburg, South Africa M16 (Pretoria), a Metropolitan Route in Pretoria, South Africa M16 (Durban), a Metropolitan Route in Durban, South Africa M16 (Bloemfontein), a Metropolitan Route in Bloemfontein, South Africa M-16 (Michigan highway), now part of U.S. Route 16 M16 motorway, former designation for parts of the M25 in England M-16 motorway (Pakistan), also known as the Swat Expressway M16 road (Zambia) M16 road (Malawi) Highway M16 (Ukraine)
Other uses M-16 (album), from German band Sodom Messier 16, a nebula also called the Eagle Nebula and its associated star cluster M16, a postcode in the M postcode area that covers part of Greater Manchester, England Mercedes-AMG F1 M16 E Performance, a 2025-spec Formula One power unit
See also M16C, a model of microcontroller by Renesas MI6, with a capital "I" instead of the digit "1", the British Secret Intelligence Service