Hypersensitivity (also called hypersensitivity reaction or intolerance) is an undesirable and adverse immune response to an antigen.

Hypersensitivity or hypersensitive may also refer to: Hypersensitivity, or Sensory Processing Sensitivity, a psychological condition relating to sensitivity to processing information. Hypersensitization, a cellular increase in the expression of a specific receptor Dentin hypersensitivity, a cause of dental pain Hyperesthesia, abnormal increase in sensitivity to stimuli of the senses Electromagnetic hypersensitivity Hypersensitive, a music album Hypersensitive response, infection defense in plants Hypersensitive site, a region in chromatin Sensory overload, experiencing overstimulation Sensory processing disorder (SPD), a medical condition relating to abnormal multisensory integration

See also Supersensitivity (disambiguation)