Karl Holz may refer to:
Karl Holz (Nazi) (1895–1945), Nazi Party leader of Gau Franconia and an SA Gruppenführer Karl Holz (violinist) (1798–1858), Austrian violinist in the Schuppanzigh Quartet Karl Holz (executive), former president of Disney Cruise Line
See also Karl Holtz (1899–1978), German artist and cartoonist