Desnoyers is a surname. Notable people with the surname include:
Auguste Gaspard Louis Desnoyers (1800–1887), French engraver Caleb Desnoyers (born 2007), Canadian ice hockey player Daniel Desnoyers, Canadian radio host and DJ Elliot Desnoyers (born 2002), Canadian ice hockey player Jules Desnoyers (1800–1887), French geologist and archaeologist Luc Desnoyers (born 1950), Canadian politician Peter J. Desnoyers (1772–1846), Detroit silversmith and businessman Peter Desnoyers (1800–1880), Detroit businessman and politician
See also Charles Desnoyer (1806–1858), French actor, playwright and theatre manager