Pregnenolone 16α-carbonitrile (PCN) is a synthetic, steroidal antiglucocorticoid and pregnane X receptor agonist. Synthesis 16-DPA is reacted with potassium cyanide to give a 68% crop of needles.B. Ellis, V. Petrow and D. Wediake, J. Chem. Soc, 3748 (1958). doi:10.1039/jr9580003715. See also Pregnenolone Mifepristone Ketoconazole Dexamethasone
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