Maniu is a Romanian surname. Notable people with the surname include:
Adrian Maniu (1891–1968), Romanian poet, prose writer, playwright, essayist, and translator Clara Maniu (1842–1929), Romanian feminist and suffragist Ioan Maniu (1833–1895), Transylvanian Romanian lawyer, politician, and journalist Iuliu Maniu (1873–1953), Austro-Hungarian-born lawyer and Romanian politician