Segre, Segrè or Segré is a Jewish-Italian surname, possibly tracing back to Sephardi communities from the area of the Segre River, Spain, or to the French town of Segré; it is concentrated in the areas of Turin, Milan and Rome. Notable people with the surname include:
Andrea Segre (born 1976), Italian film director Beniamino Segre (1903–1977), Italian mathematician Bruno Segre (1918–2024), Italian lawyer, journalist, politician and partisan Cesare Segre (1928–2014), Italian philologist, semiotician and literary critic Corrado Segre (1863–1924), Italian mathematician Dino Segre (1893–1975), known as Pitigrilli, Italian journalist and novelist Emilio Segrè (1905–1989), Italian-American chemist, physicist and Nobel laureate Giacomo Segre (1839–1894), Italian military officer Gino Segrè (born 1938), Italian-American physicist and academic (1881–1945), Jewish Italian entrepreneur and member of the Fascist Party Jacob Segrè, American distance runner Jacopo Segre (born 1997), Italian footballer Julie Segre, American geneticist Liliana Segre (born 1930), Italian Holocaust survivor and senator for life Luigi Segre (1919–1963), Italian automobile designer Paul Segre, American business executive Sion Segre Amar (1910–2003), Italian Holocaust survivor and writer
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