Louis Mathieu may refer to:
Louis-Mathieu Langlès (1763–1824), French academic, philologist, linguist, translator, author, librarian and orientalist Ludwik Mateusz Dembowski (1768-1812), Polish general and traveler Louis-Mathieu Molé (1781–1855), French statesman Claude-Louis Mathieu (1783–1875), French astronomer Louis Mathieu Verdilhan (1875–1928), French artist