1980–81 Algerian Cup

The 1980–81 Algerian Cup is the 19th edition of the Algerian Cup. USK Alger defeated ASM Oran in the final, 2-1 after extra time. All three goals in the match were scored in the 95th minute or later. It was USK Alger's first time winning the cup, after losing the final seven times (1969, 1970, 1971, 1972, 1973, 1978, and 1980).

EP Sétif were the defending champions, but they lost to DNC Alger in the quarterfinals.

Round of 64