Pithey is a surname. Notable people with the surname include:
Croye Pithey (1895–1920), South African World War I flying ace David Pithey (1936–2018), Rhodesian cricketer Jack William Pithey (1903–1984), Rhodesian politician Tony Pithey (1933–2006), Rhodesian cricketer Wensley Pithey (1914–1993), South African-born British actor