The 1906 Michigan Agricultural Aggies football team was an American football team that represented Michigan Agricultural College (now known as Michigan State University) as a member of the Michigan Intercollegiate Athletic Association (MIAA) during the 1906 college football season. In their fourth year under head coach Chester Brewer, the Aggies compiled a 7–2–2 record (7–1–1 in MIAA games), shut out six of their eleven opponents, and outscored all opponents by a total of 195 to 32.

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