George of Guria may refer to:
George I Gurieli (died 1512), duke of the duchy of Guria from 1483 to 1491, later prince of the principality of Guria from 1491 to 1512. George II Gurieli (died 1600), prince of Guria from 1564 to 1583 and again from 1587 to 1600. George III Gurieli (died 1684), prince of Guria from 1664 to 1684. George IV Gurieli (died 1726), prince of Guria from 1711 to 1726.