Patriarch Nicholas of Alexandria may refer to:

Patriarch Nicholas I of Alexandria, Greek Patriarch of Alexandria in 1210–1243 Patriarch Nicholas II of Alexandria, Greek Patriarch of Alexandria in 1263–1276 Patriarch Nicholas III of Alexandria, Greek Patriarch of Alexandria in 1389–1398 Patriarch Nicholas IV of Alexandria, Greek Patriarch of Alexandria in 1412–1417 Patriarch Nicholas V of Alexandria, Greek Patriarch of Alexandria in 1936–1939 Patriarch Nicholas VI of Alexandria, Greek Orthodox Patriarch of Alexandria in 1968–1986