The 2000–01 LEN Champions League was the 38th edition of LEN's premier competition for men's water polo clubs. It ran from 2000 to 19 May 2001, and it was contested by 8 teams. The Final Four (semifinals, final, and third place game) took place on May 18 and May 19 in Dubrovnik.
Preliminary round
Key to colors in group tablesGroup winners and runners-up advanced to Final four
Blue Group
Red Group
Final Four (Dubrovnik) Bazen u Gružu, Dubrovnik, Croatia
Final standings
Team Jug Dubrovnik Olympiacos Posillipo Bečej
Goran Volarević, Tihomil Vranješ, Đani Pecotić, Igor Računica, Ognjen Kržić, Mile Smodlaka, Dragan Medan, Ivo Ivaniš, Alen Bošković, Andrey Belofastov, Maro Balić, Elvis Fatović, Frano KaračHead coachVeselin Đuho
See also 2000–01 LEN Cup Winners' Cup 2000–01 LEN Cup