The leukotriene (LT) receptors are G protein-coupled receptors that bind and are activated by the leukotrienes. They include the following proteins:
Leukotriene B4 receptors (BLTRs) – bind to and are activated by LTB4: BLT1 (Leukotriene B4 receptor 1) – BLT2 (Leukotriene B4 receptor 2) – Cysteinyl leukotriene receptors (CysLTRs) – bind to and are activated by LTC4, LTD4, and LTE4: CysLT1 (Cysteinyl leukotriene receptor 1) – CysLT2 (Cysteinyl leukotriene receptor 2) –
The recently elucidated CysLTE, represented by GPR99/OXGR1, may constitute a third CysLTR.
See also Eicosanoid receptor Oxoeicosanoid receptor Prostaglandin receptor Thromboxane receptor
References
External links IUPHAR GPCR Database – Leukotriene receptors