Urusi was a civitas and ancient episcopal see of the Roman province of Africa Proconsularis in present-day Tunisia.

The town flourished from 30BC until 640ADR. B. Hitchner Urusi at Pleiades: A Gazetteer of Past Places (2012). and has been tentatively identified with ruins at Henchir Soudga, ()R. Cagnat and A. Merlin, Atlas archéologique de la Tunisie (1:100, 000), (Paris, 1914–32). p.30.10Barrington Atlas: BAtlas 33 E1. in Siliana Governorate. The ruins lie just outside the Jebel Serj National Park.

Bishopric The town was made famous by the courage of the martyr Mansuetus of Urusi, who was burned alive, according to Victor of VitaVictor of Vita, History of the persecution by the Vandals, I, 3. at the gate of Urusi. In 305, during the same persecution the basilicas of Lemsa, Zama and Furni, Tunisia had been burned.

The diocese was established in 1933 as a titular see.Annuario Pontificio 2013 (Libreria Editrice Vaticana, 2013, ), "Sedi titolari", pp. 819-1013

Leadership Known bishops Mansuetus, bishop of Urusi Quintianus of Urusi fl.484 Titular bishops and archbishops William Thomas Porter, 1933–1950 Teófilo José Pereira de Andrade, 1951–1954 Peter Bernard Pereira 1955–1966 Dante Frasnelli Tarter, 1967–1977 Celso José Pinto da Silva 1978–1981 José Carlos Castanho de Almeida 1982–1987 Luca Brandolini, 1987–1993 Jesús Esteban Catalá Ibáñez 1996–1999 José María Libório Camino Saracho 1999–2002 Buenaventura Malayo Famadico 2002–2003 Julian Charles Porteous 2003–2013 Jose Elmer Imas Mangalinao 2016-2018 Aquilino Bocos Merino, C.M.F. 2018 Luis Cabrera Herrera 2024–

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