D.565 is a long north–south state road from İğneada on the Black Sea to İzmir in western Turkey. The route is broken into two parts by the Sea of Marmara: a long section in East Thrace from İğneada to Tekirdağ and a section in Anatolia from Bandırma to İzmir. The gap is connected by a car ferry operating between the two port cities. The route is mostly a four-lane highway except for the first section at its northern end.

In two separate sections, the D.565 runs concurrently with two other state roads in East Thrace: with the D.020 between Poyralı and Pınarhisar and with the D.100 between Lüleburgaz and Büyükkarıştıran.

Main intersections East Thrace Province District km mi Destination Notes Kırklareli Demirköy 0.0 0.0 (İğneada Rd.) — Limanköy Pınarhisar 61 — Istanbul Eastern end of concurrency with D.020 73 — Edirne Western end of concurrency with D.020 Lüleburgaz 96 — Edirne, Istanbul Toll entrance/exit 102 — Kapıkule Western end of concurrency with D.100 120 — Istanbul Eastern end of concurrency with D.100 Tekirdağ Muratlı 132 — Çeneköy Tekirdağ 153 — Silivri, İpsala

Anatolia Province District km mi Destination Notes Balıkesir Bandırma 0.0 0.0 Port of Bandırma Carferry crosses the Sea of Marmara to D.565 in East Thrace. — Çanakkale Northern end of concurrency with D.200 Atatürk Cd. — Bursa Southern end of concurrency with D.200 — Manyas Susurluk — Karacabey — Gebze, İzmir Under construction (2019) Balıkesir — Gebze, İzmir Toll entrance/exit — Şamlı — Edremit, Kütahya Northern end of the Balıkesir Beltway, cloverleaf interchange — Sındırgı Southern end of the Balıkesir Beltway, cloverleaf interchange — Savaştepe — Sındırgı Manisa Kırkağaç 0.0 0.0 — Kırkağaç — Bakır Akhisar — Sındırgı — Bergama — Palamut — Salihli Saruhanlı — Gebze, İzmir Toll entrance/exit — Hacıveliler Manisa — Turgutlu Mimar Sinan Blv. — Manisa Northern end of the Manisa Beltway — Menemen Mimar Sinan Blv. — Manisa Southern end of the Manisa Beltway İzmir Bornova 0.0 0.0 — Çeşme, Afyon Half Y-interchange

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