ADB-CHMINACA (also known as ADMB-CHMINACA and MAB-CHMINACA) is an indazole-based synthetic cannabinoid. It is a potent agonist of the CB1 receptor with a binding affinity of Ki = 0.289 nM and was originally developed by Pfizer in 2009 as an analgesic medication. It was identified in cannabinoid blends in Japan in early 2015.
Side effects
There have been a number of reported cases of deaths and hospitalizations in relation to this synthetic cannabinoid.
Legal status In the United States, ADB-CHMINACA is a Schedule I controlled substance. Prior to its listing at the federal level in 2018, Louisiana placed ADB-CHMINACA on its Schedule I list by emergency scheduling in 2014.
Sweden's public health agency suggested to classify ADB-CHMINACA as hazardous substance on November 10, 2014.
ADB-CHMINACA is listed in the Fifth Schedule of the Misuse of Drugs Act (MDA) and therefore illegal in Singapore as of May 2015.
ADB-CHMINACA is illegal in Switzerland as of December 2015.
Metabolism Ten ADB-CHMINACA major metabolites were identified in several incubations with cryopreserved human hepatocytes. Most transformations occurred at the cyclohexylmethyl tail of the compound.
See also
5F-AB-PINACA 5F-ADB 5F-AMB 5F-APINACA AB-FUBINACA AB-CHFUPYCA AB-CHMINACA AB-PINACA ADB-BINACA ADB-FUBINACA ADB-HEXINACA ADB-PINACA ADBICA APICA APINACA MDMB-CHMICA MDMB-CHMINACA MDMB-FUBINACA PX-3
References