53rd Brigade or 53rd Infantry Brigade may refer to:
China 53rd Mountain Motorized Infantry Brigade (People's Republic of China)
Greece 53rd Brigade (Greece) of the Greek Army during the Greek Civil War
India 53rd Indian Brigade of the British Indian Army in the First World War 53rd Indian Infantry Brigade of the British Indian Army in the Second World War
Russia 53rd Anti-Aircraft Missile Brigade of the Russian Ground Forces
Ukraine 53rd Mechanized Brigade (Ukraine)
United Kingdom 53rd Brigade (United Kingdom) of the British Army during the First and Second World Wars Artillery units 53rd (Howitzer) Brigade, Royal Field Artillery of the British Army in the First World War 53rd (Bolton) Brigade, Royal Field Artillery of the British Army after the First World War 53rd (City of London) Anti-Aircraft Brigade, Royal Garrison Artillery 53rd (London) Medium Brigade, Royal Garrison Artillery
United States 53rd Infantry Brigade Combat Team
See also 53rd Division (disambiguation) 53rd Regiment (disambiguation)