Boca de Cupé is a corregimiento in Pinogana District, Darién Province, Panama with a population of 1,167 as of 2010. Its population as of 1990 was 901; its population as of 2000 was 902.
The town is not served by any paved roads, with the Pan-American Highway to the north ending at Yaviza. It is reachable by boat up the Tuira River. Civilians are not permitted to travel further east towards Colombia.Moon Central America (2016) ("Travel up the Rio Tuira beyond Boca de Cupe is considered dangerous and has been off-limits for several years. Boca de Cupe itself has a border-police post, but that doesn't necessarily make it safe.")Darien Travel Guide, Rough Guides, Retrieved 29 November 2022
In the early 1900s, a single-gauge railway ran to the town from the Cana gold mines.Karsten, Matthew (17 September 2019). The Day I Was Kicked Out of a Panamanian Village, Expert Vagabond It ceased operating in 1911.(25 December 1926). Gold Areas of the Province of Panama, in Engineering and Mining Journal, p. 1027
Villages within the corregimiento further up the river include Sobiaquirú.(1 March 2018). ARAP participa de Gira Interinstitucional en Sobiaquirú, provincia de Darién, La Autoridad de Recursos Acuáticos de Panamá (Translated sentence from Spanish: "The place of destination was the indigenous population of Sobiaquirú located in Alto Tuira of the Corregimiento of Boca de Cupe, province of Darién.")
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