Artifex may refer to:

Biology Artifex (spider), a South Pacific genus of spiders Cecidoses artifex, a moth of the family Cecidosidae Exoletuncus artifex, a species of moth of the family Tortricidae Pisidium artifex, a species of freshwater clam in the family Sphaeriidae

Other uses , a repair ship of the Royal Navy Artifex Gallery, an art gallery in Taos, New Mexico Artifex Software, an American company developing Ghostscript and MuPDF software Artifex, a 2025 album by Ancient Bards