Lewkowicz is a surname of Polish origin, often Polish-Jewish, related to Lefkowitz.
It can refer to the following persons: Josef Lewkowicz (1926–2024), Polish-born Holocaust survivor and Nazi hunter Sampson Lewkowicz (born 1951), an Uruguayan-American boxing promoter and manager Sara Naomi Lewkowicz, an American photographer Sev Lewkowicz (born 1951), an English musical composer, producer, arranger and keyboard player