Röthlisberger is a surname. Notable people with the surname include:
Hans Röthlisberger (1923–2009), Swiss glaciologist Jürg Röthlisberger (born 1955), Swiss judoka Kurt Röthlisberger (born 1951), Swiss football referee Ursula Röthlisberger (born 1964), Swiss scientist Nadia Röthlisberger-Raspe (1972–2015), Swiss curler
See also Roethlisberger (surname)