SM2 or SM-2 may refer to:
Media Films Spider-Man 2, the second Spider-Man film released in 2004 Superman II, the second Superman film released in 1980 Scary Movie 2, the second Scary Movie film released in 2001
Interactive Super Mario Bros. 2, a 1988 Nintendo Entertainment System game Warhammer 40,000: Space Marine 2
Music Spiritual Machines 2, the Our Lady Peace album released in 2021
Places SM2, the SM postcode area covering Belmont, South Sutton and East Ewell in England
Technology Military Pindad SM2, an Indonesian general purpose machine gun Standard Missile 2, either of two US missiles: RIM-66 Standard (SM-1MR/SM-2MR), a medium-range surface-to-air missile, the successor of the RIM-24 Tartar missile RIM-67 Standard (SM-1ER/SM-2ER non-VLS capable), an extended range surface-to-air missile, the successor of the RIM-2 Terrier missile SM-2, Royal Navy Second Submarine Squadron (motto: "Second to None") Hunter-Killer boats based at HMNB Devonport
Software SM-2 (algorithm), one of the computer algorithms used in SuperMemo SM2, a Chinese signature and encryption algorithm, see SM9 (cryptography standard).
Transport VR Class Sm2, a type of commuter train in Finland PZL SM-2, a Polish light utility helicopter also known as the WSK SM-2
Other Song Meter SM2, a bird monitoring recorder from Wildlife Acoustics SM-2, a research nuclear reactor at Russia's Research Institute of Atomic Reactors