Janse van Rensburg is a South African surname. Notable people sharing this surname include:
Benhard Janse van Rensburg (born 1997), South African rugby union player Brent Janse van Rensburg (born 1980), South African rugby union coach Hector Janse van Rensburg (born 1993), British painter Jacques Janse van Rensburg (born 1987), South African cyclist JC Janse van Rensburg (born 1986), South African rugby union footballer Jennifer Janse van Rensburg (born 1993), German ice dancer Johannes Frederik Janse van Rensburg (1898–1966), South African lawyer Jono Janse van Rensburg (born 1989), South African rugby union player Jurinus Janse van Rensburg (born 1952), South African military commander Lang Hans Janse van Rensburg (1779–1836), South African leader Libbie Janse van Rensburg (born 1994), South African rugby union and sevens player Nico Janse van Rensburg (born 1994), South African rugby union player Reinardt Janse van Rensburg (born 1989), South African road bicycle racer Rohan Janse van Rensburg (born 1994), South African rugby union player Rhyno Janse van Rensburg (born 1991), South African cricketer Siener Janse van Rensburg (1864–1926), South African prophet Willem Cornelis Janse van Rensburg (1818–1865), South African politician William G. L. Janse van Rensburg (1939–2008), mayor of Johannesburg