Víctor Casco de Mendoza was a Spanish nobleman in the 16th century. He held political posts during the Viceroyalty of Peru, serving as alcalde, regidor and lieutenant governor of Buenos Aires and Asunción.
Biography He was born in Asunción, the son of Gonzalo Casco, a Spanish conquistador, born in Asturias, and María de Mendoza Irala, belonging to a noble family of Asunción. He was married to Luisa de Valderrama, daughter of Juan de Fustes and Beatriz Ramírez.
Víctor Casco de Mendoza was one of the sixty-three neighbors who accompanied Juan de Garay in the second foundation of Buenos Aires.
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