Temistocle is an Italian male given name, which is derived from Themistocles. The name may refer to:
Temistocle Calzecchi-Onesti (1853–1922), Italian physicist Temistocle Popa (1921–2013), Romanian composer Temistocle Solera (1815–1878), Italian opera composer and librettist Temistocle Testa (1897–1949), Italian politician Temistocle Zammit (1864–1935), Maltese archaeologist Temistocle Zona (1848–1910), Italian astronomer