Little Brook may refer to:
Little Brook, New Jersey, an unincorporated community located within Lebanon Township in Hunterdon County, New Jersey, United States Little Brook, Nova Scotia, a community located in the Clare Municipal District in Digby County, Nova Scotia, Canada
See also Little Flat Brook, a tributary of Flat Brook in Sussex County, New Jersey in the United States Littlebrook Power Station in Dartford, Kent Lord Littlebrook (1929–2016), professional name of the British midget wrestler Eric Tovey