This is a list of artists with the most number-ones on the U.S. Billboard Dance Club Songs chart. Madonna currently holds the record for the most number-one songs in the 43-year history of the chart, with 50. The only other artists to have achieved more than 20 chart toppers are Rihanna (33) and Beyoncé (22). Janet Jackson has accumulated 20 number-ones during her career, followed by Katy Perry with 19, and Jennifer Lopez with 18. Mariah Carey and Kristine W are tied with 17. Donna Summer has 16, Lady Gaga has 15, while Dave Audé, Enrique Iglesias, Pitbull, Kylie Minogue, David Guetta, and Whitney Houston have attained 14 apiece. Two acts have attained thirteen number-one songs: Deborah Cox and Yoko Ono (aka ONO).

First: Madonna (50)

American singer-songwriter and producer Madonna has achieved a record-extending 50 number-one songs on the U.S. Billboard Dance Club Songs chart. In addition to this feat, she also holds the record for the most chart hits, the most top-twenty hits, the most top-ten hits (her overall tally as of 2020 is 62 songs placed on this chart). and the most total weeks at number one. She is the only living and active artist to continue charting at Dance Club Songs (), spanning 37 years, the longest of any artist on this chart. In its December 10, 2016, issue celebrating the 40th anniversary of the Dance Club Songs chart, Madonna ranked 1st among the top 100 all-time artists in this category.Greatest of All Time Top Dance Club Artists from Billboard (December 1, 2016) She also became the first Dance Club Songs artists in the history of the charts to have a single reach number one in five decades (1980s, 1990s, 2000s, 2010s, and 2020s).“ Madonna Achieves Milestone 50th No. 1 on Dance Club Songs Chart With 'I Don't Search I Find'” from Billboard (February 14, 2020)

Madonna's first two dance chart entries, "Everybody" in 1982 and "Burning Up" in 1983, both peaked at number three. Her first chart-topper came later in 1983, when the double-sided 12-inch single "Holiday"/"Lucky Star" spent five weeks at the summit. This remains as Madonna's longest-running number-one. Her second album Like a Virgin produced three chart-toppers during 1984–1985: "Like a Virgin", "Material Girl", and "Angel"/"Into the Groove". "Into the Groove", originally recorded for the film Desperately Seeking Susan, was later added to the Like a Virgin album when it was re-issued in non-American territories. "Open Your Heart", and "Causing a Commotion" were both number-ones in 1987. The remix album You Can Dance topped the club songs chart in 1988 (Billboard policy at the time allowed full albums or EPs to chart). Madonna closed out the 1980s with three more number-ones from her album Like a Prayer: The title track, "Express Yourself", and "Keep It Together" (in early 1990).

"Vogue" became Madonna's eleventh dance number-one in 1990, followed by "Justify My Love" in 1991. Her Erotica album produced three more chart-toppers ("Erotica", "Deeper and Deeper" and "Fever"). By the time the Bedtime Stories album spun off two more number-ones ("Secret" and "Bedtime Story"), Madonna had more number-ones than any other artist in the history of the chart. Dance remixes of "Don't Cry for Me Argentina", from the Evita soundtrack, gave Madonna her eighteenth number-one in 1997. In the late 1990s she continued to top the chart with "Frozen", "Ray of Light", "Nothing Really Matters", and "Beautiful Stranger". A cover version of Don McLean's "American Pie" hit number one in 2000.

Madonna's Music album became the first from the artist to produce four number-one dance hits: "Music", "Don't Tell Me", "What It Feels Like for a Girl", and "Impressive Instant". She bested this with her American Life album, with seven singles released during 2002–2004, five of which reached number one ("Die Another Day", "American Life", "Hollywood", "Nothing Fails", and "Love Profusion"). In the midst of this string, Madonna had another chart-topper — her only as a featured artist — on Britney Spears's "Me Against the Music" in 2003. She again produced four chart-toppers from an album, when "Hung Up", "Sorry", "Get Together", and "Jump" (from Confessions on a Dance Floor) became dance number-ones during 2005–2006. A collaboration with Justin Timberlake, "4 Minutes", became Madonna's thirty-eighth number-one in 2008, followed by "Give It 2 Me" (both from the Hard Candy album). A career retrospective, Celebration, gave her a record-extending 40th number-one ("Celebration").

Madonna's MDNA gave her three more number-one dance hits: "Give Me All Your Luvin'" (featuring Nicki Minaj and M.I.A.), "Girl Gone Wild", and "Turn Up the Radio". Madonna has collected three number-one songs from her thirteenth studio album, Rebel Heart. "Living for Love" became her forty-fourth number-one for the chart issue dated March 7, 2015. Billboard noted that it was a "historic" milestone, as Madonna tied with country singer George Strait for the most number-ones of any Billboard chart, who accumulated the same tally on the U.S. Hot Country Songs chart between 1982 and 2009. "Living for Love" also brought the singer's total amount of U.S. number-ones across all Billboard charts to 173, which includes multiple rankings. "Ghosttown" became her record-breaking forty-fifth chart topper for the issue dated May 30, 2015, breaking her tie with Strait and becoming the act with the most number-one hits on a singular Billboard chart. At the time, Madonna had garnered more number-ones on the chart than Rihanna and Beyoncé combined (45 total). It ascended to the peak with remixes by Don Diablo, Armand Van Helden, and Mindskap. "Bitch I'm Madonna" featuring Nicki Minaj became her record-extending forty-sixth chart topper in August 2015. It is Madonna's second collaboration with Minaj to reach the summit, following "Give Me All Your Luvin in 2012, and Minaj's fifth song in total to hit number one.

The singer's most recent number one entries are the four singles from her Madame X album: 2019's "Medellín", a collaboration with singer Maluma in June; "I Rise" in August; and "Crave" (featuring Rae Sremmurd member Swae Lee) in November; and February 2020 single "I Don't Search I Find". They extended her consecutive streak of number ones to ten, surpassing her two previous seven chart topping streaks (from 1987's "Causing a Commotion" to 1991's "Justify My Love", and from 1999's "Nothing Really Matters" to 2001's "Impressive Instant")"Madonna Earns 48th No. 1 on Dance Club Songs Chart With 'I Rise'" from Billboard (August 26, 2019) That feat gave Madonna her ninth number one during the 2010s (2010-2019), and she has earned three number ones each from her last three studio albums, with each triple tallied in a single year. from Billboard (February 13, 2020)"Madonna Adds 49th No. 1 on Dance Club Songs Chart With Swae Lee Collab 'Crave'"

Second: Rihanna (33)

Barbadian singer-songwriter Rihanna has achieved 33 number-one songs on the U.S. Billboard Dance Club Songs chart. Rihanna's first number-one song was her debut single "Pon de Replay" in October 2005. It was followed by three number-ones from her second album A Girl like Me; "SOS" in May 2006, "Unfaithful" in July 2006, and "We Ride" in February 2007. Her third studio album, Good Girl Gone Bad spawned four number-ones; the lead single, "Umbrella" featuring Jay-Z, peaked atop the chart for two consecutive weeks, and was followed by "Don't Stop the Music", "Shut Up and Drive" and "Disturbia". Her fourth album, Rated R charted three number one songs: "Russian Roulette", "Hard" featuring Jeezy and "Rude Boy". With "Hard" reaching the top spot, Rihanna logged to shortest time span of reaching ten number-one songs, doing so in four years and five months. However, Lady Gaga broke this record in August 2011, achieving 10 in just two years, five months and three weeks.

Rihanna's fifth album, Loud, garnered three number-ones: "Only Girl (In the World)", "S&M" and "California King Bed". In between the release of "Only Girl (In the World)" and "S&M", "Who's That Chick?", a song by David Guetta on which Rihanna features, became her thirteenth chart topper in February 2011. Rihanna's sixth studio album, Talk That Talk, once again produced three number-one songs; "We Found Love" featuring Calvin Harris peaked atop the chart for two consecutive weeks, and "You da One" and "Where Have You Been" in February and June 2012, respectively. "Diamonds", the lead single from Rihanna's seventh studio album Unapologetic, gave the singer her nineteenth number-one song in December 2012, placing her in joint second place with Janet Jackson.

"Right Now", featuring Guetta, became Rihanna's twentieth number-one in August 2013, breaking her tie with Jackson and putting her alone in the position of second place. It also meant that the singer had collected twenty number one songs in less than eight years. "Right Now" reached the top spot in its sixteenth week on the chart, and ties for the longest climb to the peak position this century, matching "Where Have You Been" as well as "Most Precious Love" by Blaze presents U.D.A.U.F.L. featuring Barbara Tucker. "What Now" became her twenty-first chart-topper in November 2013. "Can't Remember to Forget You", a song by Shakira on which Rihanna features, became her twenty-second in total; it became only the second time whereby she was not the lead artist, the other being "Who's That Chick?". Rihanna's "Bitch Better Have My Money" became her twenty-third chart topper in June 2015.

In 2016 Rihanna released Anti. The album produced eight chart toppers chart — "Work" (featuring Drake), "Kiss It Better", "Needed Me", "Love on the Brain", "Sex with Me", "Pose", "Desperado" and "Consideration" — surpassing Katy Perry's Teenage Dream (2010) as the album with the most number-one songs on that chart. Between "Pon de Replay" and "Work", Rihanna had tallied more number-ones than any other artist, besting Beyoncé with 20, Katy Perry with 15 and Madonna with 13. Rihanna earned her twenty-fifth hit with Calvin Harris' song "This Is What You Came For" on which she features in July 2016. The second and third singles from Anti, "Kiss It Better" and "Needed Me", both topped the chart. Rihanna became the first lead act in the history of the chart to have two songs in the top three due to "Needed Me" charting at number three the same week.

"Needed Me" was her twenty-seventh number-one song; her fourth hit in 2016. The fourth single from Anti, "Love on the Brain", became her twenty-eighth number-one song in January 2017, while the non-single track "Sex with Me" became her twenty-ninth three months later. It is also the fifth song from Anti to reach number-one, making it the first album to produce as many since Katy Perry's album Prism throughout 2013–2014. Between "Work" and "Sex with Me" (April 2016-April 2017), Rihanna had achieved six number-one songs while no other artist had achieved more than two in the same time span. "Pose", another non-single track from Anti, topped the chart in July 2017, becoming her thirtieth in total and her sixth from Anti. The following month, in August 2017, "Wild Thoughts" which featured Rihanna topped the dance chart, making her the sole artist to have four number-ones in five calendar years. In January 2018, "Consideration" feat. SZA became the record eighth Anti song to hit number one, surpassing the previous record holder: Perry's Teenage Dream with seven.

Third: Beyoncé (22)