CRS-2 may refer to:
SpaceX CRS-2, SpX-2, flight for SpaceX's uncrewed Dragon cargo spacecraft Cygnus CRS Orb-2, CRS-2, flight for Orbital Sciences Cygnus cargo spacecraft NASA Commercial Resupply Services — Phase 2 List of heliports in Canada#188, Parry Sound Medical Heliport (CRS2)
See also CRS (disambiguation)