Ophthalmopone is a ponerine genus of ants found in Sub-Saharan Africa. Workers are slender and large in size (8–13.5 mm). Queens seem to be absent, but gamergates (reproductive female workers) present.

Species Ophthalmopone berthoudi Forel, 1890 Ophthalmopone depilis Emery, 1902 Ophthalmopone hottentota (Emery, 1886) Ophthalmopone ilgii Forel, 1894 Ophthalmopone mocquerysi Emery, 1902

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