Pamphile was the legendary first weaver of silk in Greek tradition.

Pamphile may also refer to: Pamphile (card game), also called Mistigri, an old French card game Pamphile of Epidaurus, first-century historian Père Pamphile, fictional character in Abbé Jules by Octave Mirbeau (1888)

See also Pamphilus (disambiguation) Saint-Pamphile, Quebec