Cypriot men’s football teams have participated in UEFA competitions since the 1963–64 season. Before that, the Cyprus Football Association joined UEFA in 1962. Cypriot teams have participated in five European competitions: the European Cup/UEFA Champions League, UEFA Cup/UEFA Europa League, UEFA Cup Winners' Cup, UEFA Intertoto Cup and UEFA Europa Conference League. 16 different Cypriot clubs have participated in at least in one European competition.

In the first few decades of participation, Cypriot teams lost by large margins. Later, results began to improve. In 2006 Ethnikos Achnas became joint winner of the UEFA Intertoto Cup 2006 with 11 other teams and In 2008, a Cypriot team, Anorthosis Famagusta FC, qualified for the group stage of a European competition for the first time. Since then, at least one Cypriot team has participated in the group stage of a European tournament every season. The best performance was the appearance of APOEL FC in the quarter-finals of the 2011–12 UEFA Champions League. APOEL would also make an appearance in the round of 16 of the 2016–17 UEFA Europa League, the second best performance of a Cypriot team in UEFA competitions.

Cyprus' UEFA coefficient at the end of the 2012–13 season was 14th, the highest the country ever achieved.

European Cup/UEFA Champions League Cypriot teams began participating in the European Cup (renamed the UEFA Champions League in 1992) in 1963. The first team to do so was Anorthosis Famagusta FC against FK Partizan in Belgrade on 11 September 1963.

In this competition only the Cypriot Champions have taken part, except in the 2014–15 season, when, due to Cyprus’ UEFA coefficient ranking, the country had two participants.

Cypriot teams have taken part in the competition every season since 1963 with three exceptions: 1964–65 season: The Cyprus championship was abandoned and no team was crowned champion. 1974–75 season: As a result of the Turkish invasion of Cyprus, the three teams that qualified for European competitions withdrew. In the European Cup that team was Omonia. In the 1994–95 and 1996–97 seasons Cyprus did not receive a Champions League place due to a low country coefficient. The champions (Apollon and APOEL respectively) took part in the UEFA Cup.

Eight different Cypriot teams have taken part in the competition. On five occasions one team took part in the group stage of the Champions League. Anorthosis were the first team that took part in the group stage, in the 2008–09 UEFA Champions League. APOEL were the participants on the other four occasions. The team that has progressed furthest was APOEL in the 2011–12 season, who reached the quarter-finals.

The table presents the statistics of Cypriot teams in the competition.

+Statistics of Cypriots teams at European Cup/UEFA Champions League. Home Away Total Team APOEL FC 17 90 19 21 11 13 64 51 74 5 15 25 28 67 30 26 26 38 92 118 104 AC Omonia 18 48 6 11 5 8 42 30 38 4 1 19 19 76 13 15 6 27 61 106 51 Anorthosis Famagusta FC 8 36 8 10 5 3 36 17 35 2 4 12 11 27 10 12 9 15 47 44 45 Pafos FC 1 14 1 3 3 1 12 10 12 4 2 1 6 2 14 7 5 2 18 12 26 AEL Limassol 3 10 2 4 0 1 7 7 12 1 1 3 1 11 4 5 1 4 8 18 16 Apollon Limassol FC 3 8 1 2 1 1 6 3 7 0 0 4 1 10 0 2 1 5 7 13 7 AEK Larnaca FC 1 2 0 0 1 0 1 1 1 0 1 0 1 1 1 0 2 0 2 2 2 Olympiakos Nicosia 3 6 0 0 1 2 2 19 1 0 0 3 2 17 0 0 1 5 4 36 1 Pezoporikos Larnaca FC 1 2 0 0 0 1 1 2 0 0 0 1 1 5 0 0 0 2 2 7 0 Aris Limassol FC 1 2 0 0 0 1 0 1 0 0 0 1 1 2 0 0 0 2 0 3 0 EPA Larnaca FC 1 2 0 0 0 1 0 6 0 0 0 1 0 10 0 0 0 2 0 16 0 Total 57 220 37 51 27 32 171 147 180 16 24 70 71 228 72 67 51 102 242 375 252

For purposes of comparison the calculated rating system used is: win = 3 points, draw = 1 point, defeat = 0 points.

The table presents the participation of Cypriot teams in the competitions per season.

UEFA Cup/Europa League Cypriot teams began to participate to UEFA Cup (which renamed to UEFA Europa League at 2009) at 1971. The first team who participated was Digenis. From 1971 until 1999 only the second team of Cypriot First Division was taking part. In two season, beside the second team, the champions team also took part due to low country coefficient. Since 1999, at the competition take part also the winner of Cyprus Cup and nowadays more that two Cypriot teams are taking part to the competition. Furthermore, in many occasions the Cyprus champions, after eliminated from Champions League continue to UEFA Cup/Europa League.

Only in 1974–75 season no Cypriot team took part to the competition. As a result of Turkish invasion of Cyprus, the three teams that qualified to European competition withdrew. In UEFA Cup that team was Pezoporikos.

Fifteen different teams took part in the competition. The Cypriot teams had seven participation to the group stage. AEK was the first team that participated in the group stage at 2011–12 UEFA Europa League. The rest six participations came from APOEL (3), Apollon (2) and AEL (1). Most successful team was APOEL of 2016–17 season that qualifies and participated to round of 16.

The table presents the statistic of Cypriot teams in the competition.

+Statistics of Cypriots teams at UEFA Cup/UEFA Europa League. Home Amay Total Team APOEL FC 19 92 16 21 10 14 65 59 73 14 9 24 56 67 51 35 19 38 121 126 124 AC Omonia 20 78 18 20 11 8 73 38 71 11 8 20 46 62 41 31 19 28 119 100 112 Apollon Limassol FC 14 69 11 16 8 11 62 51 56 8 6 20 39 66 33 25 14 30 101 117 89 Anorthosis Famagusta FC 18 59 12 14 3 12 46 34 45 9 2 19 32 74 29 23 5 41 78 108 74 AEK Larnaca FC 6 38 9 12 4 3 31 12 40 7 5 7 27 27 26 19 9 10 58 39 66 AEL Limassol 5 18 2 4 1 4 15 8 13 2 2 5 6 16 8 6 3 9 21 24 21 Olympiakos Nicosia 2 6 1 0 2 1 4 8 2 1 0 2 5 18 3 1 2 3 9 26 5 Ethnikos Achna FC 1 4 1 1 1 0 5 0 4 0 0 2 2 5 0 1 1 2 7 5 4 Pezoporikos Larnaca FC 3 6 0 0 2 1 5 8 2 0 0 3 1 12 0 0 2 4 6 20 2 APOP Kinyras FC 1 2 0 0 1 0 2 2 1 0 0 1 1 2 0 0 1 1 3 4 1 Ermis Aradippou FC 1 2 0 0 0 1 0 2 0 0 0 1 0 1 0 0 0 2 0 3 0 EPA Larnaca FC 2 4 0 0 0 2 0 2 0 0 0 2 0 4 0 0 0 4 0 6 0 Digenis Akritas Morphou FC 1 2 0 0 0 1 0 3 0 0 0 1 0 4 0 0 0 2 0 7 0 Alki Larnaca FC 1 2 0 0 0 1 0 9 0 0 0 1 0 3 0 0 0 2 0 12 0 Enosis Neon Paralimni FC 2 4 0 0 0 2 3 6 0 0 0 2 1 15 0 0 0 4 4 21 0 Total 95 378 69 86 43 59 305 234 301 52 31 107 212 372 187 138 74 166 517 606 488

For purposes of comparison the calculated rating system used is: win = 3 points, draw = 1 point, defeat = 0 points.Updated as of end of 2020–21 UEFA Europa League

The table presents the participation of Cypriot teams in the competitions per season.

UEFA Cup Winners' Cup Cypriot teams participated to UEFA Cup Winners' Cup from 1963–64 season until 1998–99 season when the competition was abolished. At the competition only the Cypriot Cup winner was taking part or the finalist of the cup if the cup winner was also the champion (so had qualified to European Cup/UEFA Champions League).

The first match of a Cypriot team in any European competition was in 1963–64 European Cup Winners' Cup, when APOEL faced SK Gjøvik-Lyn at GSP Stadium (1902). Ten different teams had taken part to the competition. The best result came from Apollon Limassol at the last season of the competition, at 1998–99 UEFA Cup Winners' Cup, when for the first time a Cypriot team eliminated two teams and participated in the second round.

Only in 1974–75 season no Cypriot team took part in the competition. As a result of Turkish invasion of Cyprus, the three teams that qualified to European competition withdrew. In UEFA Cup Winners' Cup that team was Enosis Neon Paralimni.

The table presents the statistic of Cypriot teams in the competition.

+Statistics of Cypriots teams at UEFA Cup Winners' Cup. Home Amay Total Team APOEL10305528201417141076476618277824 Apollon6162224914810773633211165011 Omonia5121105511311421242197237 AEK141110504002030112534 AEL36011133400311201144154 Enosis Neon Paralimni24010134300211101034153 Pezoporikos36002112200312300242252 Anorthosis36001218100302600151341 Nea Salamis120001020001030002050 Olympiakos120001160001020002180 Total3588911924486442353619192141414606725656

For purposes of comparison the calculated rating system used is: win = 3 points, draw = 1 point, defeat = 0 points.

The table presents the participation of Cypriot teams in the competitions per season.

+Cypriot football clubs in UEFA Cup Winners' Cup. Season Team Round Opponent Country Home Away Agg. Result1963–64APOELPreliminarySK Gjøvik-LynNorway6–01–07–0First RoundSporting Clube de PortugalPortugal0–2CW21–161–181964–65AnorthosisPreliminaryAC Sparta PragueCzech RepublicCW30–6CW10–100–161965–66OmoniaFirst RoundOlympiacos F.C.Greece0–11–11–21966–67ApollonFirst RoundStandard LiègeBelgium0–1CW11–51–61967–68ApollonFirst RoundGyőri ETO FCHungary0–4CW10–50–91968–69APOELFirst RoundDunfermline Athletic F.C.Scotland0–21–101–121969–70APOELFirst RoundLierse S.K.Belgium0–1CW21–101–111970–71PezoporikosFirst RoundCardiff City F.C.Wales0–00–80–81971–72AnorthosisFirst RoundK. Beerschot V.A.C.Belgium0–1CW20–70–81972–73PezoporikosFirst RoundCork Hibernians F.C.Ireland1–2CW21–42–61973–74PezoporikosFirst Round Malmö FFSweden0–00–110–111974–75Enosis Neon ParalimniFirst RoundFC Avenir BeggenLuxembourgWithdrew due to Turkish invasion of Cyprus1975–76AnorthosisFirst RoundFC Ararat YerevanArmeniaCW41–10–91–101976–77APOELFirst RoundIraklisGreece2–00–02–0Second RoundS.S.C. NapoliItaly1–10–21–31977–78OlympiakosFirst RoundFC Universitatea CraiovaRomania1–60–21–81978–79APOELFirst RoundShamrock Rovers F.C.Ireland0–10–20–31979–80APOELPreliminaryBoldklubben 1903Denmark0–10–60–71980–81OmoniaFirst RoundK. Waterschei S.V. Thor GenkBelgium1–30–41–71981–82Enosis Neon ParalimniFirst RoundVasas SCHungary1–00–81–81982–83ApollonFirst RoundFC BarcelonaSpain1–10–81–91983–84Enosis Neon ParalimniFirst RoundK.S.K. BeverenBelgium2–41–33–71984–85APOELFirst RoundServette FCSwitzerland0–31–31–61985–86AELFirst RoundDukla PragueCzech RepublicCW32–20–42–61986–87ApollonFirst RoundMalmö FFSweden2–10–62–71987–88AELPreliminaryFC DAC 1904 Dunajská StredaSlovakiaCW50–11–51–61988–89OmoniaFirst RoundPanathinaikos F.C.Greece0–10–20–31989–90AELFirst RoundFC Admira Wacker MödlingAustria1–00–31–31990–91Nea SalamisFirst RoundAberdeen F.C.Scotland0–20–30–51991–92OmoniaFirst RoundClub Brugge KVBelgium0–20–20–41992–93ApollonFirst RoundLiverpool F.C.England1–21–62–81993–94APOELPreliminaryBangor F.C.Northern Ireland2–11–13–2First RoundParis Saint-Germain F.C.France0–10–20–31994–95OmoniaPreliminaryCS Tiligul-Tiras TiraspolMoldova3–11–03–1First RoundArsenal F.C.England1–30–31–61995–96APOELPreliminaryNeftçi PFKAzerbaijan3–00–03–0First RoundDeportivo de La CoruñaSpain0–00–80–81996–97AEKPreliminaryFC KotaykArmenia5–00–15–1First RoundFC BarcelonaSpain0–00–20–21997–98APOELPreliminaryHavnar BóltfelagFaroe Islands6–01–17–1First RoundSK Sturm GrazAustria0–10–30–41998–99ApollonPreliminaryFK EkranasLithuania3–32–15–4First RoundFK JablonecCzech Republic2–11–2 (4–3 pen)3–3Second RoundPanionios F.C.Greece0–12–32–4

CW1: The home matches of Cypriot teams were not take place in Cyprus but in their opponents country, but not at opponents' ground. CW2: The home matches of Cypriot teams were not take place in Cyprus but in their opponents country, at opponents' ground. CW3: The Czech teams was represented Czechoslovakia. CW4: The Armenian teams was represented Soviet Union. CW5: The Slovak team was represented Czechoslovakia.

UEFA Intertoto Cup UEFA Intertoto Cup was taken over by UEFA at 1995. That season the Cypriot teams began to participate in the competition, until 2008 when the competition abolished. Only in 1999 UEFA Intertoto Cup no Cypriot team took part.

In the middle of every football season, any Cypriot teams wanted to take part in Intertoto, declare their nomination and the one of them that finished in the highest position at Cypriot First Division qualified to Intertoto Cup.