Měcholupy may refer to places in the Czech Republic:
Měcholupy (Louny District), a market town in the Ústí nad Labem Měcholupy (Plzeň-South District), a municipality and village in the Plzeň Region Měcholupy, a village and part of Předslav in the Plzeň Region Dolní Měcholupy, a municipal district in Prague Horní Měcholupy, a municipal district in Prague