Lossa can refer to:
Lossa, Finne, a village in Saxony-Anhalt, Germany Lossa, Thalwitz, a village in Saxony, Germany Lossa (Mulde), a river of Saxony, Germany, tributary of the Mulde Lossa (Unstrut), a river of Saxony-Anhalt and Thuringia, Germany, tributary of the Unstrut Lossa Engineering, a motorcycle manufacturer in California