Bonomi is an Italian surname. Notable people with the surname include:
Andrea Bonomi (1923–2003), Italian footballer Andrea Bonomi (philosopher) (1940–2025), Italian philosopher and logician Beniamino Bonomi (born 1968), Italian canoer Carlo Bonomi (1937–2022), Italian voice actor Claudio Bonomi (born 1972), Italian footballer Eduardo Bonomi (1948–2022), Uruguayan guerrilla member and politician Giosuè Bonomi (born 1978), Italian road bicycle racer Giovanni Francesco Bonomi (1536–1587), Roman Catholic bishop and apostolic nuncio Gisella Bonomi (born 2000), Argentine Beach handball player Giuseppe Bonomi (1913–1992), Italian football player Ignatius Bonomi (1787–1870), English architect Ivanoe Bonomi (1873–1951), Italian prime minister Joseph Bonomi the Elder (1739–1808), English architect Joseph Bonomi the Younger (1796–1878), English sculptor Massimo Bonomi (born 1967), Italian rugby union player and sports manager Mauro Bonomi (born 1972), Italian footballer Roberto Bonomi (1919–1992), Argentine racing driver Ruggero Bonomi (1898–1980), Italian Air Force general Simone Bonomi (born 1980), Italian footballer
See also Samuel Bonom (1912–1962), New York politician Bonomini, a surname